Research
Numerous research studies have been conducted on chronic fatigue syndrome (CFS), also known as chronic fatigue and immune dysfunction syndrome (CFIDS). Most of the research has involved the search for a cause, efficacious treatment, prevalence rates and demographic characteristics.

Research articles and abstracts are available on the The CFIDS Association of America Web site or by contacting the Association.

Suggested Reading

• The 1994 International Case Definition, albeit a research definition, provides a diagnostic framework for clinicians.
• A recent prevalence study conducted by researchers at DePaul University and published in the Archives of Internal Medicine  documents that 800,000 Americans may have CFS and disputes earlier assumptions that CFS is found primarily in well-to-do, educated, young, white females.
• Chronic Fatigue Syndrome: New Insights and Old Ignorance. Evengard B; Schacterle RS; Komaroff AL. J Intern Med 1999 Nov;246 (5):455-469. 
• Doctor-Patient Relationship in Primary Care of Chronic Fatigue Syndrome: Perspectives of the Doctor and Patient. Prins, J; Bleijenberg G; Rouweler, EK; van Weel C; van der Meer JWM. J CFS 2000; Vol 7(4):3-15. 
• Chronic Fatigue Syndrome: Current Concepts of Pathogenesis and Treatment. Lloyd AR; Hickie I; Peterson PK. Curr Clin Top Infect Dis; 19:135-59.
• Dysregulated expression of tumor necrosis factor in chronic fatigue syndrome: interrelations with cellular sources and patterns of soluble immune mediator expression. Patarca R, Klimas NG, Lugtendorf S, Antoni M, Fletcher MA. Clin Infect Dis 1994 Jan; 18 Suppl1:S147-53.
• Chronic Fatigue Syndrome and Depression: Biological Differentiation and Treatment. Jorge C, Goodnick P. Psych Annal May 1997; 27:5: 365-371. Available at The CFIDS Association store.